TL13-22
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TL13-22

SKU T37084-1 mg Category Brand:

Price range: 526 CAD through 3,568 CAD

Products Details

Product Description

– TL13-22 is a potent inhibitor of Anaplastic Lymphoma Kinase (ALK) with an IC₅₀ value of 0.54 nM and does not lead to degradation of ALK proteins.TL13-22 is often used as a negative control for TL13-12 (induces ALK protein degradation) as a negative control.TL13-22 also induces degradation of other kinases, including Aurora A, FER, PTK2, and RPS6KA1.

Web ID

– T37084

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C45H55ClN10O9S

References

– Powell et al (2018) Chemically induced degradation of anaplastic lymphoma kinase (ALK). J.Med.Chem. 61 4249 PMID:29660984

CAS Number

– 2229036-65-9

Molecular Weight

– C45H55ClN10O9S

Compound Purity

– 0.9913

SMILES

– O=C1C=2C=CC=C(NCC(=O)NCCOCCOCCN3CCN(C4=CC=C(NC5=NC=C(Cl)C(=N5)NC=6C=CC=CC6S(=O)(=O)C(C)C)C(OC)=C4)CC3)C2C(=O)N1C7C(=O)NCCC7

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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