Timosaponin AIII
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Timosaponin AIII

SKU T3395-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 1,195 CAD

Products Details

Product Description

– Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC50: 2.5 μM, BT474 cells; 6 μM, MDAMB231). The Timosaponin AIII pro-apoptotic response is selective for tumor cells over normal cells but autophagy is induced in both.

Web ID

– T3395

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C39H64O13

References

– Wu ZT, et al. Acta Pharmacol Sin. 2014 Sep;35(9):1188-98.

CAS Number

– 41059-79-4

Molecular Weight

– C39H64O13

Compound Purity

– 0.9961

SMILES

– C[C@@]12[C@@]3([C@](C[C@]1([C@]4([C@](CC2)([C@]5(C)[C@](CC4)(C[C@@H](O[C@H]6[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@@H](O)[C@@H](CO)O6)CC5)[H])[H])[H])[H])(O[C@@]8([C@H]3C)CC[C@H](C)CO8)[H])[H]

Pathway

– Neuroscience|||PI3K/Akt/mTOR signaling

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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