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THZ2
$115 – $1,540
Products Details
Product Description
– THZ2 is a potent and selective CDK7 inhibitor with an IC50 of 13.9 nM.
Web ID
– HY-12280
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C31H28ClN7O2
References
– [1]Wang Y, et al. CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer. Cell. 2015 Sep 24;163(1):174-186.
CAS Number
– 1604810-84-5
Molecular Weight
– 566.05
Compound Purity
– 99.03
SMILES
– O=C(NC1=CC=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2)=C1)C5=CC=CC(NC(/C=C/CN(C)C)=O)=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 21.67 mg/mL (ultrasonic)
Target
– CDK
Isoform
– CDK1;CDK2;CDK5;CDK7;CDK8;CDK9
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
