THZ2
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THZ2

SKU T7296-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 123 CAD through 1,322 CAD

Products Details

Product Description

– THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).

Web ID

– T7296

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H28ClN7O2

Citations

– 1. Jiang L, Yu Y, Li Z, et al.BMS-265246, a Cyclin-Dependent Kinase Inhibitor, Inhibits the Infection of Herpes Simplex Virus Type 1.Viruses.2023, 15(8): 1642.

References

– Huang JR, Qin WM, Wang K,et al.Cyclin-dependent kinase 7 inhibitor THZ2 inhibits the growth of human gastric cancer in vitro and in vivo.Am J Transl Res. 2018 Nov 15;10(11):3664-3676.

CAS Number

– 1604810-84-5

Molecular Weight

– C31H28ClN7O2

Compound Purity

– 0.9828

SMILES

– CN(C)CC=CC(=O)Nc1cccc(c1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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