THR-β agonist 6
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THR-β agonist 6

SKU T74785-5 mg Category Brand:

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Products Details

Product Description

– THR-β Agonist 6, a selective and orally active compound targeting the thyroid hormone receptor β (THR-β), demonstrates specificity with EC50 values of 0.03 μM for THR-β and 0.22 μM for THR-α. This compound boasts a remarkable liver-to-serum ratio of 93:1 in mouse models, underscoring its efficacy and potential for research in nonalcoholic steatohepatitis (NASH) [1].

Web ID

– T74785

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H14Cl2N6O3

CAS Number

– 2791290-58-7

Molecular Weight

– C20H14Cl2N6O3

SMILES

– ClC1=C(N2C3=C(C=C2)N(C(C)C)C(=O)C=C3)C(Cl)=CC(=C1)N4N=C(C#N)C(=O)NC4=O

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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