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ThioLox
SKU
HY-139196-10 mg
Category Reference compound
Tags Inflammation/Immunology; Neurological Disease, Lipoxygenase, Metabolic Enzyme/Protease
$180 – $1,200
Products Details
Product Description
– ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with a Ki of 3.30 μM. ThioLox shows anti-inflammatory and neuroprotective properties[1].
Web ID
– HY-139196
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H18N2OS
References
– [1]Eleftheriadis N, et al. Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties. Eur J Med Chem. 2016 Oct 21;122:786-801.
CAS Number
– 1202193-89-2
Molecular Weight
– 274.38
Compound Purity
– 99.97
SMILES
– O=C(C1=C(N)SC(C2=CC=CC=C2)=C1)NCCCC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Lipoxygenase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.