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Thiamine disulfide
SKU
HY-B2224-10mM/1mL
Category Reference compound
Tags Anti-infection;Metabolic Enzyme/Protease, Endogenous Metabolite;HIV, Infection; Metabolic Disease
$50 – $55
Products Details
Product Description
– Thiamine disulfide, a vitamin B1 derivative, is an oxidized dimer of Thiamine. Thiamine disulfide is a potent HIV-1 inhibitor. Thiamine disulfide significantly depresses HIV-1 transactivator (Tat) activity[1][2].
Web ID
– HY-B2224
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C24H34N8O4S2
References
– [1]S Shoji, et al. Thiamine disulfide as a potent inhibitor of human immunodeficiency virus (type-1) production. Biochem Biophys Res Commun. 1994 Nov 30;205(1):967-75.|[2]Y Komata, et al. In vitro percutaneous absorption of thiamine disulfide from a mixture of propylene glycol and fatty acid. J Pharm Sci. 1992 Aug;81(8):744-6.
CAS Number
– 67-16-3
Molecular Weight
– 562.71
Compound Purity
– 98.05
SMILES
– C/C(N(CC1=CN=C(C)N=C1N)C=O)=C(SS/C(CCO)=C(N(CC2=CN=C(C)N=C2N)C=O)C)/CCO
Clinical Information
– Launched
Research Area
– Infection; Metabolic Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Endogenous Metabolite;HIV
Isoform
– HIV-1
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.