Download Files:
Thalidomide-NH-PEG4-COOH
$1,350 – $2,250
Products Details
Product Description
– Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].
Web ID
– HY-134591
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H31N3O10
References
– [1]Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4.
CAS Number
– 2412056-48-3
Molecular Weight
– 521.52
Compound Purity
– 98.55
SMILES
– O=C(C1=CC(NCCOCCOCCOCCOCCC(O)=O)=CC=C12)N(C3CCC(NC3=O)=O)C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 80 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
