Download Files:
Tetrabenazine Metabolite
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– Tetrabenazine Metabolite is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a high affinity (Ki=13.4 nM)[1]. Tetrabenazine Metabolite is be developed for the treatment of chorea associated with Huntington’s disease and other hyperkinetic disorders[1].
Web ID
– HY-G0025
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C19H29NO3
References
– [1]Yao Z, et al. Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors. Eur J Med Chem. 2011 May;46(5):1841-8.
CAS Number
– 924854-60-4
Molecular Weight
– 319.44
SMILES
– O[C@H]([C@H](CC(C)C)C1)C[C@@]2([H])N1CCC3=C2C=C(OC)C(OC)=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite;Monoamine Transporter
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
