Download Files:
Terbinafine-d3 (hydrochloride)
$470
Only 1000 item(s) left in stock.
Products Details
Product Description
– Terbinafine-d3 (hydrochloride) is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM[1][2]. Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria[3].
Web ID
– HY-17395S
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Molecular Formula
– C21H23D3ClN
References
– [1]Ciftci E, et al. Mupirocin vs terbinafine in impetigo.Indian J Pediatr. 2002 Aug;69(8):679-82.|[2]Mieth H, et al. Preclinical evaluation of terbinafine in vivo. Clin Exp Dermatol. 1989 Mar;14(2):104-8.|[3]Ryder NS, et al. Terbinafine: mode of action and properties of the squalene epoxidase inhibition. Br J Dermatol. 1992 Feb;126 Suppl 39:2-8.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1310012-15-7
Molecular Weight
– 330.91
Compound Purity
– 99.0
SMILES
– CC(C)(C)C#C/C=C/CN(C([2H])([2H])[2H])CC1=CC=CC2=C1C=CC=C2.Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 10 mg/mL (ultrasonic;warming)|Ethanol : 30 mg/mL (ultrasonic;warming)
Target
– Antibiotic;Bacterial;Fungal;Isotope-Labeled Compounds
Pathway
– Anti-infection;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
