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Teprotumumab
Price range: 261 CAD through 2,384 CAD
Products Details
Product Description
– Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab reduces TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used in the study of thyroid-associated eye diseases.
Web ID
– T76727
Storage Temperature
– -20℃
Shipping
– Blue Ice
References
– Chen H, et al. Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes. J Clin Endocrinol Metab. 2014 Sep;99(9):E1635-40.
CAS Number
– 1036734-93-6
Molecular Weight
Compound Purity
– 99.6% (SEC-HPLC)
Pathway
– Tyrosine Kinase/Adaptors|||GPCR/G Protein
Product type
– Inhibitory Antibodies
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
