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Products Details
Product Description
– Tenovin-3 is a p53 activator[1][2].
Web ID
– HY-19339
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H21N3OS
References
– [1]Jifei Miao, et al. Nuclear HMGB1 promotes the phagocytic ability of macrophages. Exp Cell Res. 2020 Aug 1;393(1):112037.|[2]Lain S, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63.
CAS Number
– 1011301-27-1
Molecular Weight
– 327.44
Compound Purity
– 99.86
SMILES
– O=C(NC(NC1=CC=C(N)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 31 mg/mL
Target
– MDM-2/p53
Pathway
– Apoptosis
Product type
– Reference compound
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