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Telenzepine (dihydrochloride)
SKU
HY-B1789A-10 mg
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mAChR, Neurological Disease
$95 – $450
Products Details
Product Description
– Telenzepine dihydrochloride is a selective and orally active muscarinic M1 receptor antagonist with a Ki of 0.94 nM. Telenzepine dihydrochloride inhibits gastric acid secretion and has antiulcer effects[1][2][3].
Web ID
– HY-B1789A
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H24Cl2N4O2S
References
– [1]R Riedel, et al. Comparison of the gastric antisecretory and antiulcer potencies of telenzepine, pirenzepine, ranitidine and cimetidine in the rat. Digestion. 1988;40(1):25-32.|[2]F L Christofi, et al. Neuropharmacology of the muscarinic antagonist telenzepine in myenteric ganglia of the guinea-pig small intestine. Eur J Pharmacol. 1991 Apr 3;195(3):333-9.|[3]M Galvan, et al. Interaction of telenzepine with muscarinic receptors in mammalian sympathetic ganglia. Eur J Pharmacol. 1989 Aug 11;167(1):1-10.
CAS Number
– 147416-96-4
Molecular Weight
– 443.39
Compound Purity
– 99.08
SMILES
– O=C1C2=CSC(C)=C2N(C(CN3CCN(C)CC3)=O)C4=CC=CC=C4N1.[H]Cl.[H]Cl
Clinical Information
– Phase 1
Research Area
– Neurological Disease
Solubility
– H2O : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– mAChR
Isoform
– mAChR1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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