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Tegobuvir
$350 – $1,800
Products Details
Product Description
– Tegobuvir is a specific, covalent inhibitor of the HCV NS5B polymerase.
Web ID
– HY-10544
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C25H14F7N5
References
– [1]Wong KA, et al. Tegobuvir (GS-9190) potency against HCV chimeric replicons derived from consensus NS5B sequences from genotypes 2b, 3a, 4a, 5a, and 6a.
Virology. 2012 Jul 20;429(1):57-62.|[2]Bae AS, et al. Allele-specific real-time PCR system for detection of subpopulations of genotype 1a and 1b hepatitis C NS5B Y448H mutant viruses in clinical samples.
J Clin Microbiol. 2011 Sep;49(9):3168-74.|[3]Hebner CM, et al. The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function.
PLoS One. 2012;7(6):e39163.
CAS Number
– 1000787-75-6
Molecular Weight
– 517.40
Compound Purity
– 98.02
SMILES
– FC1=CC=CC=C1C2=NC3=CN(CC4=NN=C(C5=CC=C(C(F)(F)F)C=C5C(F)(F)F)C=C4)C=CC3=N2
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– DMSO : ≥ 50 mg/mL
Target
– HCV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
