Tecastemizole

$260$2,100

Products Details

Product Description

– Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities[1].

Web ID

– HY-105014

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C19H21FN4

References

– [1]Lever R, et al. Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses. Clin Exp Allergy. 2007 Jun;37(6):909-17.

CAS Number

– 75970-99-9

Molecular Weight

– 324.40

Compound Purity

– 99.85

SMILES

– FC1=CC=C(CN2C3=CC=CC=C3N=C2NC4CCNCC4)C=C1

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Histamine Receptor

Isoform

– H1 Receptor

Pathway

– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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