TCMDC-135051
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TCMDC-135051

SKU T13102-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 126 CAD through 3,088 CAD

Products Details

Product Description

– TCMDC-135051 is a potent and selective PfCLK3 protein kinase inhibitor demonstrating significant antiparasiticidal activity (EC50=320 nM) while exhibiting minimal off-target toxicity. It effectively hinders the transition from trophozoite to schizont, impairs transcription, and diminishes transmission to the mosquito vector.

Web ID

– T13102

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H33N3O3

References

– Alam MM, et al. Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science. 2019 Aug 30;365(6456). pii: eaau1682.

CAS Number

– 2413716-15-9

Molecular Weight

– C29H33N3O3

Compound Purity

– 0.9821

SMILES

– CCN(CC)Cc1ccc(OC)c(c1)-c1cc2c(ccnc2[nH]1)-c1ccc(C(O)=O)c(c1)C(C)C

Target

– Others

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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