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Products Details
Product Description
– TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
Web ID
– HY-132931
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H18ClN5O3
References
– [1]Chia W, et al. High-Content Phenotypic Screen of a Focused TCAMS Drug Library Identifies Novel Disruptors of the Malaria Parasite Calcium Dynamics. ACS Chem Biol. 2021 Nov 19;16(11):2348-2372.
CAS Number
– 872113-12-7
Molecular Weight
– 399.83
SMILES
– ClC1=CC(NC(CN(C(C2=NN(N=C2)C3=CC=CC=C3)=O)C)=O)=C(C=C1)OC
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
