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TB-21007
SKU
HY-103510-Get quote
Category Reference compound
Tags GABA Receptor, Membrane Transporter/Ion Channel;Neuronal Signaling, Neurological Disease
Products Details
Product Description
– TB-21007 is an inverse agonist of α5β3γ2 subunit-containing GABAA receptor with a Ki of 1.6 nM. TB-21007 enhanced spatial memory in rats[1].
Web ID
– HY-103510
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H17NO2S3
References
– [1]Chambers MS, et al. Identification of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognition. J Med Chem. 2003 May 22;46(11):2227-40.
CAS Number
– 207306-50-1
Molecular Weight
– 339.50
SMILES
– O=C1CC(C)(C)CC2=C(C3=NC=CS3)SC(SCCO)=C21
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.