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TASK-1-IN-1
$100 – $850
Products Details
Product Description
– TASK-1-IN-1 is a potent and selective TASK-1 (Potassium Channel) inhibitor with an IC50 of 148 nM. TASK-1-IN-1 shows a reduced inhibition of TASK-3 channels (IC50 of 1750 nM) and not a significant effect on other K+ channels. TASK-1-IN-1 has anticancer effects.
Web ID
– HY-151891
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H20N2O2
References
– [1]Bárbara Arévalo, et al. Selective TASK-1 Inhibitor with a Defined Structure-Activity Relationship Reduces Cancer Cell Proliferation and Viability. J Med Chem. 2022 Nov 24;65(22):15014-15027.
CAS Number
– 600125-11-9
Molecular Weight
– 344.41
Compound Purity
– 98.36
SMILES
– CCC1=CC=CC=C1NC(C2=CC=CC(NC(C3=CC=CC=C3)=O)=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 66.67 mg/mL (ultrasonic)
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
