TAS4464 hydrochloride

SKU T13090-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 98 CAD through 2,192 CAD

Products Details

Product Description

– TAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM).

Web ID

– T13090

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H24ClFN6O6S

References

– Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.

CAS Number

– 1848959-11-4

Molecular Weight

– C21H24ClFN6O6S

Compound Purity

– 0.9861

SMILES

– Cl.CCOc1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12

Target

– Others

Pathway

– Metabolism|||Ubiquitination

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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