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Taraxerol acetate
SKU
HY-N2599-1 mg
Category Natural Products
Tags Apoptosis;COX, Apoptosis;Immunology/Inflammation, Cancer
$120 – $450
Products Details
Product Description
– Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis[1].
Web ID
– HY-N2599
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C32H52O2
References
– [1]Ubaid Ur Rehman1 A, et al. Molecular docking of taraxerol acetate as a new COX inhibitor. Journal of the Bangladesh Pharmacological Society|[2]Hong JF, et al. Anticancer activity of taraxerol acetate in human glioblastoma cells and a mouse xenograft model via induction of autophagy and apoptotic cell death, cell cycle arrest and inhibition of cell migration.Mol Med Rep. 2016 Jun;13(6):4541-8.
CAS Number
– 2189-80-2
Molecular Weight
– 468.75
SMILES
– C[C@]12C3=CC[C@@](C)(CCC(C)(C)C4)[C@]4([H])[C@@]3(CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](OC(C)=O)CC5)C)([H])CC2)C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;COX
Isoform
– COX-1;COX-2
Pathway
– Apoptosis;Immunology/Inflammation
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.