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Taprenepag
$130 – $990
Products Details
Product Description
– Taprenepag (CP-544326) is a potent and selective prostaglandin EP(2) agonist with IC50s of 10 and 15 nM for human and rat EP2, respectively. Taprenepag shows selectivity for EP2 over other EP receptors (IC50s>3200 nM for EP1, EP3, and EP4) and a panel of 37 G protein-coupled receptors[1].
Web ID
– HY-14899
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C24H22N4O5S
References
– [1]Prasanna G, et al. Effect of PF-04217329 a prodrug of a selective prostaglandin EP(2) agonist on intraocular pressure inpreclinical models of glaucoma. Exp Eye Res. 2011 Sep;93(3):256-64.
CAS Number
– 752187-80-7
Molecular Weight
– 478.52
Compound Purity
– 99.54
SMILES
– O=S(C1=CN=CC=C1)(N(CC2=CC(OCC(O)=O)=CC=C2)CC3=CC=C(N4C=CC=N4)C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Prostaglandin Receptor
Isoform
– EP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
