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Products Details
Product Description
– Tanshinone IIA anhydride is a potent and irreversible human carboxylesterase (CE) inhibitor with Ki values of 1.9 nM and 1.4 nM for human CE1 and the human intestinal CE (hiCE), respectively[1].
Web ID
– HY-N10686
Shipping
– Room temperature
Molecular Formula
– C19H18O4
References
– [1]M Jason Hatfield, et al. Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza (“Danshen”). J Nat Prod. 2018 Nov 26;81(11):2410-2418.|[2]M Jason Hatfield, et al. Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza (“Danshen”). J Nat Prod. 2018 Nov 26;81(11):2410-2418.
CAS Number
– 61077-78-9
Molecular Weight
– 310.34
SMILES
– CC1(CCCC2=C1C=CC3=C2C(OC(C4=C3OC=C4C)=O)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Pathway
– Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
