SZL P1-41
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SZL P1-41

SKU T3317-1 mg Category Brand:

Price range: 48 CAD through 1,968 CAD

Products Details

Product Description

– SZL P1-41, a skp2 inhibitor, can prevent assembly of Skp2-Skp1 complexes. It selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. It also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. It suppresses the survival of Y cells and Y stem cells by triggering cell senescence and inhibiting glycolysis. It exhibits antitumor effects in multiple animal models and Y cell lines.

Web ID

– T3317

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H24N2O3S

References

– Chan et al.Cell, 2013;154:556

CAS Number

– 222716-34-9

Molecular Weight

– C24H24N2O3S

Compound Purity

– 0.9978

SMILES

– CCc1cc2c(occ(-c3nc4ccccc4s3)c2=O)c(CN2CCCCC2)c1O

Target

– TNF|||Antifection|||c-Myc|||COX

Pathway

– Ubiquitination|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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