Download Files:
SynuClean-D
SKU
HY-124876-1 mg
Category Reference compound
Tags Neurological Disease, Neuronal Signaling, α-synuclein
$214 – $3,350
Products Details
Product Description
– SynuClean-D (SC-D) is an inhibitor of α-synuclein aggregation, disrupts mature amyloid fibrils, prevents fibril propagation, and abolishes the degeneration of dopaminergic neurons in an animal model of Parkinson’s disease[1].
Web ID
– HY-124876
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C13H5F3N4O5
References
– [1]Pujols J, et al. Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486.
CAS Number
– 685121-45-3
Molecular Weight
– 354.20
Compound Purity
– 99.23
SMILES
– N#CC1=C(C(F)(F)F)C([N+]([O-])=O)=C(C2=CC=CC([N+]([O-])=O)=C2)NC1=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– α-synuclein
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.