Supinoxin
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Supinoxin

SKU T16961-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 184 CAD through 1,952 CAD

Products Details

Product Description

– Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent, inducing cell apoptosis and inhibiting the growth of TNBC cancer cell lines (IC50s: 10 nM – 20 nM).

Web ID

– T16961

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H24FN5O4

References

– Kost GC, et al. A Novel Anti-Cancer Agent, 1-(3,5-Dimethoxyphenyl)-4-[(6-Fluoro-2-Methoxyquinoxalin-3-yl)Aminocarbonyl] Piperazine (RX-5902), Interferes With β-Catenin Function Through Y593 Phospho-p68 RNA Helicase.J Cell Biochem. 2015 Aug;116(8):1595-601.

CAS Number

– 888478-45-3

Molecular Weight

– C22H24FN5O4

Compound Purity

– 0.9983

SMILES

– COc1cc(OC)cc(c1)N1CCN(CC1)C(=O)Nc1nc2cc(F)ccc2nc1OC

Target

– Antibiotic

Pathway

– Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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