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SU5408
SKU
HY-103002-1 mg
Category Reference compound
Tags Cardiovascular Disease, Protein Tyrosine Kinase/RTK, VEGFR
$108 – $1,980
Products Details
Product Description
– SU5408 (VEGFR2 Kinase Inhibitor I) is a potent and cell-permeable inhibitor of VEGFR2 kinase with an IC50 of 70 nM.
Web ID
– HY-103002
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H18N2O3
References
– [1]Sun L, et al. Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity towardparticular receptor tyrosine kinases. J Med Chem. 1998 Jul 2;41(14):2588-603.
CAS Number
– 15966-93-5
Molecular Weight
– 310.35
Compound Purity
– 98.0
SMILES
– O=C(C1=C(C)NC(/C=C2C(NC3=C2C=CC=C3)=O)=C1C)OCC
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 6 mg/mL (ultrasonic;warming)
Target
– VEGFR
Isoform
– VEGFR2/KDR/Flk-1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.