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Su1498
Price range: 54 CAD through 821 CAD
Products Details
Product Description
– Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.
Web ID
– T3980
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H30N2O2
References
– Gawlak G, et al. Chronic high-magnitude cyclic stretch stimulates EC inflammatory response via VEGF receptor 2-dependent mechanism. Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1062-70.
CAS Number
– 168835-82-3
Molecular Weight
– C25H30N2O2
Compound Purity
– 0.9954
SMILES
– CC(C)c1cc(C=C(/C#N)C(=O)NCCCc2ccccc2)cc(C(C)C)c1O
Pathway
– Tyrosine Kinase/Adaptors|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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