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Products Details
Product Description
– STING agonist-11 (Compound 92) is a potent small molecule cyclic urea activator of STING with EC50 of 18 nM. Activation of STING is a highly promising approach in immunotherapy[1].
Web ID
– HY-144329
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H20ClF4N3O2
References
– [1]Sourav Basu, et al. The discovery of potent small molecule cyclic urea activators of STING. Eur J Med Chem. 2022 Feb 5;229:114087.
CAS Number
– 2259308-68-2
Molecular Weight
– 505.89
SMILES
– O=C(C1=CC2=C(C=C1)[C@H](C)N(C)C(N2CC3=C(F)C=CC=C3Cl)=O)NCC4=C(F)C=C(F)C=C4F
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cancer
Solubility
– 10 mM in DMSO
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
