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ST271
$35 – $530
Products Details
Product Description
– ST271 is a potent inhibitor of protein tyrosine kinase (PTK), inhibits phospholipase D activation stimulated by fMet-Leu-Phe and PAF, with IC50s of 6.7 and 9 μM, respectively.
Web ID
– HY-103097
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C16H20N2O2
References
– [1]Martinson EA, et al. Inhibition of phospholipase D of human platelets by protein tyrosine kinase inhibitors. Cell Mol Biol (Noisy-le-grand). 1994 Jul;40(5):627-34.|[2]Blake RA, et al. Fc gamma receptor II stimulated formation of inositol phosphates in human platelets is blocked by tyrosine kinase inhibitors and associated with tyrosine phosphorylation of the receptor.|[3]Uings IJ, et al. Tyrosine phosphorylation is involved in receptor coupling to phospholipase D but not phospholipase C in the human neutrophil. Biochem J. 1992 Feb 1;281 (Pt 3):597-600.
CAS Number
– 106392-48-7
Molecular Weight
– 272.34
Compound Purity
– 98.90
SMILES
– O=C(N)/C(C#N)=C/C1=CC(C(C)C)=C(O)C(C(C)C)=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : ≥ 110 mg/mL
Target
– Phospholipase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
