Download Files:
Products Details
Product Description
– ST-1006 is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 has anti-inflammatory effect[1][2].
Web ID
– HY-120541
Shipping
– Room temperature
Molecular Formula
– C16H20Cl2N6
References
– [1]Adami M, et, al. Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice. Naunyn Schmiedebergs Arch Pharmacol. 2018 Dec;391(12):1387-1397.|[2]Mommert S, et, al. Human basophil chemotaxis and activation are regulated via the histamine H4 receptor. Allergy. 2016 Sep;71(9):1264-73.
CAS Number
– 1196994-11-2
Molecular Weight
– 367.28
SMILES
– ClC(C=CC=C1Cl)=C1CNC2=CC(N3CCN(CC3)C)=NC(N)=N2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor
Isoform
– H4 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
