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Products Details
Product Description
– ST-1006 is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 has anti-inflammatory effect[1][2].
Web ID
– HY-120541
Shipping
– Room temperature
Molecular Formula
– C16H20Cl2N6
References
– [1]Adami M, et, al. Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice. Naunyn Schmiedebergs Arch Pharmacol. 2018 Dec;391(12):1387-1397.|[2]Mommert S, et, al. Human basophil chemotaxis and activation are regulated via the histamine H4 receptor. Allergy. 2016 Sep;71(9):1264-73.
CAS Number
– 1196994-11-2
Molecular Weight
– 367.28
SMILES
– ClC(C=CC=C1Cl)=C1CNC2=CC(N3CCN(CC3)C)=NC(N)=N2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor
Isoform
– H4 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
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