Download Files:
SSR128129E
$70 – $550
Products Details
Product Description
– SSR128129E is an orally available and allosteric FGFR inhibitor with an IC50 of 1.9 μM for FGFR1.
Web ID
– HY-15599
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H15N2NaO4
References
– [1]Bono F, et al. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell. 2013 Apr 15;23(4):477-88.
CAS Number
– 848318-25-2
Molecular Weight
– 346.31
Compound Purity
– 99.85
SMILES
– O=C(O[Na])C1=CC(C(C2=C(C)C(OC)=C3C=CC=CN23)=O)=CC=C1N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 54 mg/mL
Target
– FGFR
Isoform
– FGFR1;FGFR2;FGFR3;FGFR4
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
