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Products Details
Product Description
– SSR-241586 is an antagonist of neurokinin receptors. SSR-241586 is shown to be active in the treatment of depression, schizophrenia, urinary trouble, emesis, and irritable bowel syndrome (IBS)[1][2].
Web ID
– HY-19456
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C32H42Cl2N4O3
References
– [1]Métro TX, et al. Asymmetric synthesis of an antagonist of neurokinin receptors: SSR 241586. J Org Chem. 2011 Apr 15;76(8):2594-602.|[2]Cochi A, et al. Enantioselective synthesis of SSR 241586 by using an organo-catalyzed Henry reaction. Org Lett. 2010 Aug 20;12(16):3693-5.
CAS Number
– 1239279-30-1
Molecular Weight
– 601.61
SMILES
– O=C(C1(N2CCCCC2)CCN(CC[C@@]3(C4=CC=C(Cl)C(Cl)=C4)CN(C(C5=CC=CC=C5)=O)CCO3)CC1)N(C)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Neurokinin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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