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(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine
$90 – $2,100
Products Details
Product Description
– (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level. (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine has a multi-path anti-fibrosis function and a renal protection function for research of renal anemia[1].
Web ID
– HY-147025
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C41H46N6O6S
References
– [1]Method for dual-target construction of protac, and use thereof. WO2020119192A1.
CAS Number
– 2347517-69-3
Molecular Weight
– 750.91
Compound Purity
– 99.06
SMILES
– O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CCC(NC(C4=CN=CC=C4)C5=CC6=CC=CC=C6O5)=O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : ≥ 170 mg/mL
Target
– HIF/HIF Prolyl-Hydroxylase;PROTACs;TGF-beta/Smad
Pathway
– Metabolic Enzyme/Protease;PROTAC;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
