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(S,R,S)-AHPC-amido-C5-acid

$390$550

Products Details

Product Description

– (S,R,S)-AHPC-amido-C5-acid incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-amido-C5-acid can be used to design XY028-133 (HY-129180)[1].

Web ID

– HY-130798

Storage Temperature

– -20°C (Powder, sealed storage, away from moisture and light)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C29H40N4O6S

References

– [1]Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1.

CAS Number

– 2162120-87-6

Molecular Weight

– 572.72

Compound Purity

– 97.84

SMILES

– O=C([C@H]1N(C[C@@H](C1)O)C([C@@H](NC(CCCCCC(O)=O)=O)C(C)(C)C)=O)NCC2=CC=C(C=C2)C3=C(N=CS3)C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– E3 Ligase Ligand-Linker Conjugates

Isoform

– von Hippel-Lindau (VHL)

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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