Products Details

Product Description

– Spns2-IN-1 is a potent inhibitor of Spns2-dependent S1P transport (Spns2), with IC50 of 1.4±0.3 μM that plays an important role in immune response[1].

Web ID

– HY-156408

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C24H40ClN3

References

– [1]Christopher W Shrader, et al. Imidazole-based sphingosine-1-phosphate transporter Spns2 inhibitors. Bioorg Med Chem Lett. 2023 Oct 11:96:129516.

Molecular Weight

– 406.05

SMILES

– CCN1C(CCCN)=NC(C2=CC=C(CCCCCCCCCC)C=C2)=C1.Cl

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– LPL Receptor

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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