Spebrutinib
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Spebrutinib

SKU T2603-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 56 CAD through 331 CAD

Products Details

Product Description

– Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton’s agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity.

Web ID

– T2603

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H22FN5O3

Citations

– 1. Jin X, Yang Y, Liu D, et al.Identification of a covalent NEK7 inhibitor to alleviate NLRP3 inflammasome-driven metainflammation.Cell Communication and Signaling.2024, 22(1): 565.

References

– Evans E, et al. ASH Annual Meeting, 2011 San Diego, CA.

CAS Number

– 1202757-89-8

Molecular Weight

– C22H22FN5O3

Compound Purity

– 0.9702

SMILES

– COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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