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SPDB
$108 – $720
Products Details
Product Description
– SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs)[1].
Web ID
– HY-12448
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C13H14N2O4S2
References
– [1]Widdison WC et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolitesin Cancer Cells andInduce High Levels of Bystander Killing.
Bioconjug Chem, 2015 Nov 18, 26(11):2261-78.
CAS Number
– 115088-06-7
Molecular Weight
– 326.39
Compound Purity
– 99.16
SMILES
– O=C(CC1)N(OC(CCCSSC2=NC=CC=C2)=O)C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 200 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)
Target
– ADC Linker
Isoform
– Cleavable Linker;Disulfide Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
