Sovilnesib

$300$2,500

Products Details

Product Description

– Sovilnesib (AMG 650) is a potent, orally active kinesin-like protein KIF18A inhibitor with an IC50 value of 0.071 μM. Sovilnesib can be used for the research of cancer[1][2].

Web ID

– HY-132840

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C26H34F2N6O4S

References

– [1]Payton MN, et, al. Kif18a inhibitors for treatment of neoplastic diseases. WO2021211549|[2]Tamayo NA, et, al. Kif18a inhibitors. WO2020132648.

CAS Number

– 2410796-79-9

Molecular Weight

– 564.65

Compound Purity

– 99.89

SMILES

– O=C(NC1=NC(N2CCC(F)(F)CC2)=NC(C)=C1)C3=CC=C(NS(=O)(CCO)=O)C=C3N(CC4)CCC54CC5

Clinical Information

– Phase 1

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Microtubule/Tubulin

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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