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SOS1-IN-18

SKU T205557-10 mg Category Brand:

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Product Description

– SOS1-IN-18 (Compound 8) is an inhibitor of the Son of Sevenless 1 protein (SOS1) with a dissociation constant (KD) of 2.6 nM. It disrupts the SOS1-KRAS G12C interaction with an IC50 of 3.4 nM, inhibits ERK phosphorylation in H358 cells with an IC50 of 31 nM, and curtails the proliferation of H358 cells with an IC50 of 5 nM.

Web ID

– T205557

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H29F3N4O2

Molecular Weight

– C26H29F3N4O2

Target

– Others

Pathway

– GPCR/G Protein|||MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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