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Products Details
Product Description
– Solifenacin D5 hydrochloride is a deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride is a muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively[1].
Web ID
– HY-135329
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H22D5ClN2O2
References
– [1]Ikeda K, et al. M(3) receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladderand salivary gland. Naunyn Schmiedebergs Arch Pharmacol. 2002 Aug;366(2):97-103.
CAS Number
– 1426174-05-1
Molecular Weight
– 403.96
SMILES
– O=C(O[C@@H]1C2CCN(CC2)C1)N3CCC4=CC=CC=C4[C@@H]3C5=C([2H])C([2H])=C([2H])C([2H])=C5[2H].[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Isoform
– mAChR1;mAChR2;mAChR3
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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