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Sodium metatungstate
$55 – $73
Products Details
Product Description
– Sodium metatungstate (Sodium polyoxotungstate) is a potent ecto-nucleoside triphosphate diphosphohydrolase (ENTPDase) inhibitor, with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively[1]. Sodium metatungstate inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition[2].
Web ID
– HY-103259
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– H2Na6O40W12
References
– [1]Müller CE, et al. Polyoxometalates–a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5943-7.|[2]Wall et al. The novel NTPDase inhibitor sodium polyoxotungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition. Neuropharmacology. 2008 Dec;55(7):1251-8.
CAS Number
– 12141-67-2
Molecular Weight
– 2986.01
Compound Purity
– 93.0
SMILES
– [3Na2WO4.9WO3]
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
Target
– Phosphatase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
