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Products Details
Product Description
– SN-38-d3 is a deuterated form of SN-38. As the active metabolite of the topoisomerase I (TopoisomeraseI) inhibitor irinotecan, SN-38 (NK012) notably inhibits the synthesis of DNA and RNA, with IC50 values of 0.077 and 1.3 μM, respectively.
Web ID
– T89645
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H20N2O5
CAS Number
– 718612-49-8
Molecular Weight
– C22H20N2O5
SMILES
– C(C([2H])([2H])[2H])C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC(O)=CC5
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Isotope products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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