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Products Details
Product Description
– SMD-3040 is a potent and selective SMARCA2 PROTAC degrader (DC50: 12 nM), comprising an SMARCA2/4 ligand, a linker, and a VHL ligand. It exhibits excellent degradation selectivity for the SMARCA2 protein over the SMARCA4 protein and has demonstrated robust tumor growth inhibition in xenograft models [1].
Web ID
– T79820
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C52H66N10O5S
CAS Number
– 3033109-92-8
Molecular Weight
– C52H66N10O5S
SMILES
– CC1=C(C2=CC=C([C@@H](NC([C@@H]3C[C@@H](O)CN3C([C@@H](NC([C@@H]4CC[C@@H](CN5CC6(CCC(N7C=C(C8=CC(C9=CC=CC=C9O)=NN=C8N)C=N7)CC6)C5)CC4)=O)C(C)(C)C)=O)=O)C)C=C2)SC=N1
Pathway
– Chromatin/Epigenetic
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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