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SM1-71
70 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– SM1-71 is a potent multi-targeted acrylamide-modified TAK1 inhibitor that inhibits MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2.SM1-71 can be used as a kinase probe with anticancer activity and inhibits the proliferation of various cancer cell lines.
Web ID
– T36680
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H26ClN7O
References
– Rao S, et, al. Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chem Biol. 2019 Jun 20; 26(6): 818-829.e9.
CAS Number
– 2088179-99-9
Molecular Weight
– C24H26ClN7O
Compound Purity
– 0.96
SMILES
– CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3ccccc3NC(=O)C=C)n2)cc1
Pathway
– Cell Cycle/Checkpoint|||MAPK|||Metabolism|||Stem Cells|||Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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