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SKA-121
SKU
HY-107414-10 mg
Category Reference compound
Tags Cardiovascular Disease, Membrane Transporter/Ion Channel, Potassium Channel
$80 – $1,100
Products Details
Product Description
– SKA-121 is a selective KCa3.1 activator. SKA-121 exhibits EC50s of 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively.
Web ID
– HY-107414
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H10N2O
References
– [1]Coleman N, et al. New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1. Mol Pharmacol. 2014 Sep;86(3):342-57.
CAS Number
– 1820708-73-3
Molecular Weight
– 198.22
Compound Purity
– 98.64
SMILES
– NC1=NC2=CC(C)=C3C=CC=CC3=C2O1
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : ≥ 42.86 mg/mL
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.