SKA-111
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SKA-111

SKU T24799-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 102 CAD through 3,440 CAD

Products Details

Product Description

– SKA-111 is a selective calcium-activated potassium phannel (potassium phannel ) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial cells.SKA-111 binds to the interface between the CaM N-valve and the S4-S5 junction and ameliorates Bradykinin-induced dilation of coronary arteries in the isolated rat heart, which can be used for the study of cardiovascular diseases. study of cardiovascular diseases.

Web ID

– T24799

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C12H10N2S

References

– Oliván-Viguera A, et al. Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed. Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):184-92.

CAS Number

– 1369170-24-0

Molecular Weight

– C12H10N2S

Compound Purity

– 0.9979

SMILES

– NC1=NC=2C=3C(C(C)=CC2S1)=CC=CC3

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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