SJ6986

SKU T41257-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 1,512 CAD

Products Details

Product Description

– SJ6986 is a potent, selective, and orally active GSPT1/2 degrader, effectively degrading GSPT1 with a DC50 of 2.1 nM (D max 99%) [1].

Web ID

– T41257

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H14F3N3O7S

References

– Nishiguchi G, et al. Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators. J Med Chem. 2021 Jun 10;64(11):7296-7311.

CAS Number

– 2765625-93-0

Molecular Weight

– C20H14F3N3O7S

Compound Purity

– 0.9945

SMILES

– O=C1N(C(=O)C=2C1=CC(NS(=O)(=O)C3=C(OC(F)(F)F)C=CC=C3)=CC2)C4C(=O)NC(=O)CC4

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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