Download Files:
Sisunatovir (hydrochloride)
$71 – $1,150
Products Details
Product Description
– Sisunatovir (RV521) hydrochloride, an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC50s of 1.4 nM and 1.0 nM, respectively[1].
Web ID
– HY-123475A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C23H23ClF4N4O
References
– [1]DeVincenzo J, et al. A Randomized, Placebo-Controlled, Respiratory Syncytial Virus Human Challenge Study of the Antiviral Efficacy, Safety, and Pharmacokinetics of RV521, an Inhibitor of the RSV-F Protein. Antimicrob Agents Chemother. 2020;64(2):e01884-19. Published 2020 Jan 27.
CAS Number
– 1903763-83-6
Molecular Weight
– 482.90
Compound Purity
– 98.54
SMILES
– O=C(N(C1=C2C=CC(F)=C1)CC3=NC4=CC(CN)=CC=C4N3CCCC(F)(F)F)C52CC5.[H]Cl
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– RSV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
