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Products Details
Product Description
– SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with an IC50 value of 2.3 μM. SIRT5 inhibitor 2 has inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 can be used for researching cancer and neurodegenerative diseases[1].
Web ID
– HY-146386
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H12Cl2N2O3S
References
– [1]Wang Y, et al. Overview of SIRT5 as a potential therapeutic target: Structure, function and inhibitors. Eur J Med Chem. 2022;236:114363.
CAS Number
– 340306-87-8
Molecular Weight
– 407.27
SMILES
– C=CCN1C(/C(C(NC1=S)=O)=C/C2=CC=C(O2)C3=CC=CC(Cl)=C3Cl)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sirtuin
Isoform
– SIRT5
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
