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Products Details
Product Description
– Sirt2-IN-5 is a potent SIRT2 inhibtor[1].
Web ID
– HY-115979
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H27Cl2N5O3
References
– [1]Sukuroglu, M.K., et al. The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking. Med Chem Res 30, 1915–1924 (2021).
CAS Number
– 902456-47-7
Molecular Weight
– 528.43
SMILES
– O=C1C(C2=CC=C(Cl)C=C2)=CC(N3CCOCC3)=NN1CC(N4CCN(C5=CC=CC(Cl)=C5)CC4)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sirtuin
Isoform
– SIRT2
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
